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The HUPO-PSI standardized spectral library format

More and more proteomics datasets are becoming available in public repositories. The knowledge embedded in these datasets can be used to improve peptide identification workflows. Spectral library searching provides a straightforward method to boost …

MS²PIP : fast and accurate MS² peak intensity prediction for multiple fragmentation methods, instruments and labeling techniques

An important step in high-throughput mass spectrometry-based proteomics is the correct identification of peptide MS² fragmentation spectra. Due to incomplete understanding of the fragmentation process and unpredictable machine noise, matching MS² …

Fast and accurate MS² peak intensity predictions for multiple fragmentation methods, instruments and labeling techniques

In mass spectrometry-based proteomics, sequence database search engines have proven to be the gold standard in peptide spectrum identification workflows. However, new demands and novel techniques, such as open modification searches and …